Intermediates

Suven Pharma manufactures intermediates for several API’s falling under a wide range of therapeutic categories used in the pharmaceutical synthesis process. We provide integrated pharmaceutical services, including the development of pharmaceutical intermediate production processes and the optimization of commercial production, as well as all registrations and filings in compliance with the regulations and guiding principles of the ICH and NMPA/FDA.

PYRIMIDINES

Pyridazines, Pyrazines, Piperazines, Piperidines, Pyrans.

Intermediates

Nucleoside Phosphoramidites

CYTIDINE, N -BENZOYL-2′,3′-DIDEOXY-3′-
[(TRIPHENYLMETHYL)AMINO]-, 5′-CYANOETHYL -N,
N –DIISOPROPYLPHOSPHORAMIDITE.

CAS: 195375-65-6
MOL FORMULA: C44H49N6O5P
MOL WEIGHT: 772.87
PURITY: NLT 97.0%

N4-BENZYL-5′-O-(4,4′-DIMETHOXYTRITYL)-2’-
DEOXYCYTIDINE-3′-CYANOETHYL-N,NDIISOPROPYLPHOSPHORAMIDITE
(DMT-DC(BN)PHOSPHORAMIDITE)

MOL FORMULA: C46H54N5O7P
MOL WEIGHT: 819.95
PURITY: NLT 98.0%

GUANOSINE, 2′,3′-DIDEOXY-N -(2-METHYL-1-OXOPROPYL)
-3′-[(TRIPHENYLMETHYL)AMINO]-, 5′- CYANOETHYLN,N -DIISOPROPYLPHOSPHORAMIDITE

CAS: 195375-66-7
MOL FORMULA: C42H51N8O5P
MOL WEIGHT: 778.88
PURITY: NLT 97.0%

N4-ACETYL-5-METHYL-5′-O-(4,4′-DIMETHOXYTRITYL)-2’-
DEOXYCYTIDINE-3′-CYANOETHYL-N,NDIISOPROPYLPHOSPHORAMIDITE
(DMT-5-MEDC(AC)PHOSPHORAMIDITE)

MOL FORMULA: C42H52N5O8P
MOL WEIGHT: 785.86
PURITY: NLT 97.0%

5’-BENZOYLTHYMIDINE-3’- CYANOETHYL
-N,N-DIISOPROPYLPHOSPHORAMIDITE

MOL FORMULA: C26H35N4O7P
MOL WEIGHT: 546.57
PURITY: NLT 98.0%

N4-ACETYL-5′-O-(4,4′-DIMETHOXYTRITYL)-2’-
DEOXYCYTIDINE-3′-CYANOETHYL-N,NDIISOPROPYLPHOSPHORAMIDITE
(DMT-DC(AC)PHOSPHORAMIDITE)

CAS: 154110-40-4
MOL FORMULA: C41H50N5O8P
MOL WEIGHT: 771.86
PURITY: NLT 98.0%

N6-BENZOYL-5′-O-(4,4′-DIMETHOXYTRITYL)- 3′-
TERTBUTYLDIMETHYLSILYLADENOSINE-2’-
CYANOETHYL-N,N-DIISOPROPYLPHOSPHORAMIDITE

CAS: 129451-75-8
MOL FORMULA: C53H66N7O8PSI
MOL WEIGHT: 988.19
PURITY: NLT 95.0%

2-CYANOETHYLTETRAISOPROPYL
PHOSPHORODIAMIDITE

CAS: 102691-36-1
MOL FORMULA: C15H32N3OP
MOL WEIGHT: 301.42
PURITY: NLT 95.0%

5’-O-DIMETHOXYTRITYLTHYMIDINE-3’-CYANOETHYL
-N,N-DIISOPROPYLPHOSPHORAMIDITE

CAS: 98796-51-1
MOL FORMULA: C40H49N4O8P
MOL WEIGHT: 744.81
PURITY: NLT 98.0%

ADENOSINE, 2′,3′-DIDEOXY-N -[(DIMETHYLAMINO)
METHYLENE]-3′-[(TRIPHENYLMETHYL)AMINO]-,
5′-CYANOETHYL -N,N –
DIISOPROPYLPHOSPHORAMIDITE

CAS: 1644649-86-4
MOL FORMULA: C41H50N9O3P
MOL WEIGHT: 747.87
PURITY: NLT 97.0%

N4-BENZOYL-5′-O-(4,4′-DIMETHOXYTRITYL)-2’-
DEOXYCYTIDINE-3′-CYANOETHYL-N,NDIISOPROPYLPHOSPHORAMIDITE (DMT-DC(BZ)
PHOSPHORAMIDITE)(AC-DC PHOSPHORAMIDITE)

CAS: 102212-98-6
MOL FORMULA: C46H52N5O8P
MOL WEIGHT: 833.93
PURITY: NLT 98.0%

THYMIDINE, 3′-DEOXY-3′-[(TRIPHENYLMETHYL)
AMINO]-, 5′-CYANOETHYL-N,N –
DIISOPROPYLPHOSPHORAMIDITE

CAS: 195375-68-9
MOL FORMULA: C38H46N5O5P
MOL WEIGHT: 683.78
PURITY: NLT 97.0%

N4-BENZOYL-5-METHYL-5′-O-(4,4′-DIMETHOXYTRITYL)-2’-
DEOXYCYTIDINE-3′-CYANOETHYL-N,NDIISOPROPYLPHOSPHORAMIDITE
(DMT-5-MEDC(BZ)PHOSPHORAMIDITE)

CAS: 105931-57-5
MOL FORMULA: C47H54N5O8P
MOL WEIGHT: 847.93
PURITY: NLT 98.0%

5’-O-TERTBUTYLDIMETHYLSILYLTHYMIDINE-3’-
CYANOETHYL-N,N-DIISOPROPYLPHOSPHORAMIDITE

MOL FORMULA: C25H45N4O6PSI
MOL WEIGHT: 556.72
PURITY: NLT 98.0%